Metabolic & Digestive Wellness Panel

Lactose Intolerance

Digestive symptoms caused by declining lactase expression after weaning; over 90% of East Asians are lactase non-persistent, with bloating, cramps and diarrhoea after dairy.

Alcohol Intolerance

About 30-50% of East Asians carry an ALDH2 variant; acetaldehyde build-up causes flushing, palpitations and headache, and markedly raises esophageal and upper digestive tract cancer risk.

Caffeine Metabolism Dysfunction

Slow CYP1A2 metabolisers clear caffeine over 9-12 hours, making palpitations, anxiety and insomnia more likely and raising cardiovascular risk at high intake.

Folate Metabolism Disorder

Reduced MTHFR activity impairs conversion of folate to active 5-MTHF, raising homocysteine and affecting fetal neural tube development during pregnancy.

Hyperhomocysteinemia

Serum homocysteine above 15 μmol/L is usually symptomless but is an independent risk factor for cardiovascular disease, stroke and cognitive decline.

Esophageal Cancer

In ALDH2 variant carriers, long-term acetaldehyde exposure after drinking sharply raises squamous cell carcinoma risk; early disease is almost symptomless, so regular endoscopy matters.

Upper Digestive Tract Cancers

Defective alcohol metabolism lets acetaldehyde accumulate in the upper digestive tract mucosa, markedly raising the risk of esophageal, gastric, oral and pharyngeal cancers.